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A Lancet Psychiatry study found GLP-1 medications were linked to a lower risk of worsening depression, anxiety, and self-harm. Not because theyre psychiatric drugs but because the brain is metabolic.
Holst: We found that not only did GLP-1 stimulate insulin secretion, it also inhibited glucagon secretion. This was interesting, because people with diabetes have too much glucagon and that glucagon causes high blood sugar.
GLP-1 drugs were found to have a powerful effect in preventing tissue damage, which has the potential to cut the risk of serious problems that affect up to half of all patients suffering a heart attack.
As we can see from the illustration, We Found That Glp has many fascinating aspects to explore.
He had also found GLP-1 (7-37) in experiments in cell lines. In February of 1987, Mojsov, Weir, and Habener published another paper showing GLP-1(7-37) stimulated insulin secretion in rat pancreases.
It has been found that individuals with type 2 diabetes are twice as likely to have depression, and having depression significantly increases the odds of developing obesity. Glucagon-like peptide-1 (GLP-1) receptor agonists are highly effective in the treatment of diabetes and obesity.
